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FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE GENE REPORT: DMEL\GLURIA The gene Glutamate receptor IA is referred to in FlyBase by the symbol Dmel\GluRIA (CG8442, FBgn0004619). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6624032..6635059. FLYBASE RECOMBINANT CONSTRUCT REPORT: P{ESG-GAL4.U} Recombinant Construct: P {esg-GAL4.U} esg sequences control expression of a GAL4 driver. esg sequences control expression of a GAL4 driver. Sox100B Regulates Progenitor-Specific Gene Expression and Cell Differentiation in the Adult Drosophila Intestine. FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE EXPERIMENTAL TOOL REPORT: CSCHRIMSON CsChrimson is a light-gated cation channel that can be used as an optogenetic tool to activate neurons; it is optimally excited by light of 590nm wavelength. It is an artificial channelrhodopsin in which the extracellular N-terminus of the Chlamydomonas noctigama CnChR1 'Chrimson' gene has been replaced with the corresponding sequence from the Chloromonas subdivisa CsChR gene FLYBASE HOMEPAGETOOLSSPECIESSEARCH/BROWSE PORTALSSUBMIT DATAOVERVIEWEXTERNAL RESOURCES Experiments with Drosophila for Biology Courses. Experiments with Drosophila for Biology Courses, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics FLYBASE GENE REPORT: DMEL\DPY dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and FLYBASE GENE REPORT: DMEL\MIR-14 Is expressed in organism. (Alliance, FBgn0262447 ) Automatically Generated Summary (FlyBase) The gene mir-14 stem loop is referred to in FlyBase by the symbol Dmel\mir-14 (CR43013, FBgn0262447). It is a miRNA_gene from Dmel. It has 3 annotated transcripts. FLYBASE BALANCER/GENOTYPE VARIANT REPORT: DMEL\FM7A The Genome of Drosophila melanogaster. Rasooly et al., 1991, Genetics 129: 409--422. The lethal (1)TW6 cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-bindingdomain.
FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE GENE REPORT: DMEL\GLURIA The gene Glutamate receptor IA is referred to in FlyBase by the symbol Dmel\GluRIA (CG8442, FBgn0004619). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6624032..6635059. FLYBASE RECOMBINANT CONSTRUCT REPORT: P{ESG-GAL4.U} Recombinant Construct: P {esg-GAL4.U} esg sequences control expression of a GAL4 driver. esg sequences control expression of a GAL4 driver. Sox100B Regulates Progenitor-Specific Gene Expression and Cell Differentiation in the Adult Drosophila Intestine. FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE EXPERIMENTAL TOOL REPORT: CSCHRIMSON CsChrimson is a light-gated cation channel that can be used as an optogenetic tool to activate neurons; it is optimally excited by light of 590nm wavelength. It is an artificial channelrhodopsin in which the extracellular N-terminus of the Chlamydomonas noctigama CnChR1 'Chrimson' gene has been replaced with the corresponding sequence from the Chloromonas subdivisa CsChR gene FLYBASE REFERENCE REPORT: HAKES AND BRAND, 2020, ELIFE 9 Understanding the sequence of events leading to cancer relies in large part upon identifying the tumour cell of origin. Glioblastoma is the most malignant brain cancer but the early stages of disease progression remain elusive. FLYBASE ALLELE REPORT: DMEL\W w 1118 mutant flies exhibit memory performance levels that are approximately 60% of wild-type levels in a heat-box. w 1118 mutants have approximately 30% of wild-type levels of serotonin and dopamine. Octopamine levels are approximately 80% of wild-type levels. ( Sitaraman et al., 2008) FLYBASE REFERENCE REPORT: BOOMGARDEN ET AL., 2019, BMC Circadian clocks are found in nearly all organisms, from bacteria to mammals, and ensure that behavioral and physiological processes occurat optimal times of
FLYBASE GENE REPORT: DMEL\CHIC The gene chickadee is referred to in FlyBase by the symbol Dmel\chic (CG9553, FBgn0000308). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is 2L:5972115..5981018. Its molecular function is described by: protein binding; actin monomer binding. FLYBASE GENE REPORT: DMEL\MEF2 Gene Summary. Myocyte enhancer factor 2 ( Mef2) encodes a protein that belongs to the MADS-box family of transcription factors and is required for muscle development. It directly activates a large number of muscle protein genes. It also regulates gene expression in other tissues, including the fat body and neural tissue. FLYBASE REFERENCE REPORT: LEE ET AL., 2019, GENE 687: 64--72 Lin-28 is a conserved RNA-binding protein that is involved in a wide range of developmental processes and pathogenesis. At the molecular level, Lin-28 blocks the maturation of let-7 and regulates translation of certain mRNA targets. FLYBASE STRAIN REPORT: CANTON-S Contains a recessive for multiple thoracic and scutellar bristles, which overlaps wild type in most flies but appears sporadically in strains partly derived from Canton-S. Selected by C. Bridges. Genetic variations of Drosophila melanogaster. FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE REFERENCE REPORT: BECHSTEDT ET AL., 2010, NAT Mechanoreceptors are sensory cells that transduce mechanical stimuli into electrical signals and mediate the perception of sound, touch andacceleration.
GENE GROUP: ESCRT-III COMPLEX The ESCRT (Endosomal Sorting Complexes Required for Transport) machinery is made up of five complexes, ESCRT-0 to -III and the Vps4-Vta1 ATPase complex, which are sequentially recruited to the cytosolic face of the membrane, and mediate cargo recognition, membrane budding and fission. ESCRT-III is a dynamic complex, that assembles on endosomes. FLYBASE HOMEPAGETOOLSSPECIESSEARCH/BROWSE PORTALSSUBMIT DATAOVERVIEWEXTERNAL RESOURCES Experiments with Drosophila for Biology Courses. Experiments with Drosophila for Biology Courses, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics FLYBASE GENE REPORT: DMEL\DPY dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and FLYBASE GENE REPORT: DMEL\MIR-14 Is expressed in organism. (Alliance, FBgn0262447 ) Automatically Generated Summary (FlyBase) The gene mir-14 stem loop is referred to in FlyBase by the symbol Dmel\mir-14 (CR43013, FBgn0262447). It is a miRNA_gene from Dmel. It has 3 annotated transcripts. FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE GENE REPORT: DMEL XF2 The gene nuclear RNA export factor 2 is referred to in FlyBase by the symbol Dmel xf2 (CG4118, FBgn0036640). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:16576859..16580306. FLYBASE BALANCER/GENOTYPE VARIANT REPORT: DMEL\FM7A The Genome of Drosophila melanogaster. Rasooly et al., 1991, Genetics 129: 409--422. The lethal (1)TW6 cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-bindingdomain.
FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE EXPERIMENTAL TOOL REPORT: CSCHRIMSON CsChrimson is a light-gated cation channel that can be used as an optogenetic tool to activate neurons; it is optimally excited by light of 590nm wavelength. It is an artificial channelrhodopsin in which the extracellular N-terminus of the Chlamydomonas noctigama CnChR1 'Chrimson' gene has been replaced with the corresponding sequence from the Chloromonas subdivisa CsChR gene FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE EXPERIMENTAL TOOL REPORT: GAL80TS The GAL80ts entry in FlyBase represents a temperature-sensitive version of the Saccharomyces cerevisiae GAL80 gene ( SGDID:S000004515 ). At the permissive temperature of 18C, GAL80ts protein is functional, acting as a negative regulator of the Saccharomyces cerevisiae GAL4 transcriptional activator, by binding to the GAL4 protein. At restrictive temperatures above 29C, FLYBASE HOMEPAGETOOLSSPECIESSEARCH/BROWSE PORTALSSUBMIT DATAOVERVIEWEXTERNAL RESOURCES Experiments with Drosophila for Biology Courses. Experiments with Drosophila for Biology Courses, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics FLYBASE GENE REPORT: DMEL\DPY dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and FLYBASE GENE REPORT: DMEL\MIR-14 Is expressed in organism. (Alliance, FBgn0262447 ) Automatically Generated Summary (FlyBase) The gene mir-14 stem loop is referred to in FlyBase by the symbol Dmel\mir-14 (CR43013, FBgn0262447). It is a miRNA_gene from Dmel. It has 3 annotated transcripts. FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE GENE REPORT: DMEL XF2 The gene nuclear RNA export factor 2 is referred to in FlyBase by the symbol Dmel xf2 (CG4118, FBgn0036640). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:16576859..16580306. FLYBASE BALANCER/GENOTYPE VARIANT REPORT: DMEL\FM7A The Genome of Drosophila melanogaster. Rasooly et al., 1991, Genetics 129: 409--422. The lethal (1)TW6 cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-bindingdomain.
FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE EXPERIMENTAL TOOL REPORT: CSCHRIMSON CsChrimson is a light-gated cation channel that can be used as an optogenetic tool to activate neurons; it is optimally excited by light of 590nm wavelength. It is an artificial channelrhodopsin in which the extracellular N-terminus of the Chlamydomonas noctigama CnChR1 'Chrimson' gene has been replaced with the corresponding sequence from the Chloromonas subdivisa CsChR gene FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE EXPERIMENTAL TOOL REPORT: GAL80TS The GAL80ts entry in FlyBase represents a temperature-sensitive version of the Saccharomyces cerevisiae GAL80 gene ( SGDID:S000004515 ). At the permissive temperature of 18C, GAL80ts protein is functional, acting as a negative regulator of the Saccharomyces cerevisiae GAL4 transcriptional activator, by binding to the GAL4 protein. At restrictive temperatures above 29C, FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE ALLELE REPORT: DMEL\W w 1118 mutant flies exhibit memory performance levels that are approximately 60% of wild-type levels in a heat-box. w 1118 mutants have approximately 30% of wild-type levels of serotonin and dopamine. Octopamine levels are approximately 80% of wild-type levels. ( Sitaraman et al., 2008) FLYBASE GENE REPORT: DMEL\ORT The gene ora transientless is referred to in FlyBase by the symbol Dmel\ort (CG7411, FBgn0003011). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19659748..19663672. FLYBASE REFERENCE REPORT: HORSFIELD ET AL., 1998 During eye development in Drosophila, cell cycle progression is coordinated with differentiation. Prior to differentiation, cells arrest in G1 phase anterior to FLYBASE REFERENCE REPORT: YANIV ET AL., 2012, CURR. BIOL The molecular mechanisms that determine axonal growth potential are poorly understood. Intrinsic growth potential decreases with age, and thus one strategy to identify molecular pathways controlling intrinsic growth potential is by studying developing young neurons. FLYBASE REFERENCE REPORT: MOHLER, 1977, GENETICS 85: 259--272 Mohler, J.D. (1977). Developmental genetics of the Drosophila egg. I. Identification of 59 sex-linked cistrons with maternal effects on embryonic development. FLYBASE REFERENCE REPORT: DATE ET AL., 1998 Date, A., Satta, Y., Takahata, N., Chigusa, S.I. (1998). Evolutionary history and mechanism of the Drosophila cecropin gene family. Immunogenetics 47(6): 417--429. FLYBASE REFERENCE REPORT: JAYANANDANAN ET AL., 2011, EMBO Jayanandanan, N., Gavis, E.R., Riechmann, V., Leptin, M. (2011). A genetic in vivo system to detect asymmetrically distributed RNA. EMBO Rep. 12(11): 1167--1174. FLYBASE REFERENCE REPORT: ARAMA ET AL., 2000, ONCOGENE 19 Inactivation of both alleles of the fruit fly D. melanogaster brain tumor (brat) gene results in the production of a tumor-like neoplasm in the larval brain, and FLYBASE REFERENCE REPORT: YIN ET AL., 2017, BMC BIOL. 15(1 Zinc is an essential metal involved in many physiological processes. Previous work has identified a set of zinc transporters involved in Drosophila dietary zinc absorption. FLYBASE HOMEPAGETOOLSSPECIESSEARCH/BROWSE PORTALSSUBMIT DATAOVERVIEWEXTERNAL RESOURCES Experiments with Drosophila for Biology Courses. Experiments with Drosophila for Biology Courses, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics FLYBASE GENE REPORT: DMEL\DPY dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and FLYBASE BALANCER/GENOTYPE VARIANT REPORT: DMEL\FM7A The Genome of Drosophila melanogaster. Rasooly et al., 1991, Genetics 129: 409--422. The lethal (1)TW6 cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-bindingdomain.
FLYBASE GENE REPORT: DMEL\MIR-14 Is expressed in organism. (Alliance, FBgn0262447 ) Automatically Generated Summary (FlyBase) The gene mir-14 stem loop is referred to in FlyBase by the symbol Dmel\mir-14 (CR43013, FBgn0262447). It is a miRNA_gene from Dmel. It has 3 annotated transcripts. FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE GENE REPORT: DMEL\STAN Automatically Generated Summary (FlyBase) The gene starry night is referred to in FlyBase by the symbol Dmel\stan (CG11895, FBgn0024836). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (5 unique). FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE RECOMBINANT CONSTRUCT REPORT: P{ESG-GAL4.U} Recombinant Construct: P {esg-GAL4.U} esg sequences control expression of a GAL4 driver. esg sequences control expression of a GAL4 driver. Sox100B Regulates Progenitor-Specific Gene Expression and Cell Differentiation in the Adult Drosophila Intestine. FLYBASE GENE REPORT: DMEL\SNU Is expressed in adult head; embryonic/larval trachea; and presumptive embryonic/larval system. (Alliance, FBgn0039594 ) The gene snustorr is referred to in FlyBase by the symbol Dmel\snu (CG9990, FBgn0039594). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (all unique). FLYBASE HOMEPAGETOOLSSPECIESSEARCH/BROWSE PORTALSSUBMIT DATAOVERVIEWEXTERNAL RESOURCES Experiments with Drosophila for Biology Courses. Experiments with Drosophila for Biology Courses, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics FLYBASE GENE REPORT: DMEL\DPY dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and FLYBASE BALANCER/GENOTYPE VARIANT REPORT: DMEL\FM7A The Genome of Drosophila melanogaster. Rasooly et al., 1991, Genetics 129: 409--422. The lethal (1)TW6 cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-bindingdomain.
FLYBASE GENE REPORT: DMEL\MIR-14 Is expressed in organism. (Alliance, FBgn0262447 ) Automatically Generated Summary (FlyBase) The gene mir-14 stem loop is referred to in FlyBase by the symbol Dmel\mir-14 (CR43013, FBgn0262447). It is a miRNA_gene from Dmel. It has 3 annotated transcripts. FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE GENE REPORT: DMEL\STAN Automatically Generated Summary (FlyBase) The gene starry night is referred to in FlyBase by the symbol Dmel\stan (CG11895, FBgn0024836). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (5 unique). FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE RECOMBINANT CONSTRUCT REPORT: P{ESG-GAL4.U} Recombinant Construct: P {esg-GAL4.U} esg sequences control expression of a GAL4 driver. esg sequences control expression of a GAL4 driver. Sox100B Regulates Progenitor-Specific Gene Expression and Cell Differentiation in the Adult Drosophila Intestine. FLYBASE GENE REPORT: DMEL\SNU Is expressed in adult head; embryonic/larval trachea; and presumptive embryonic/larval system. (Alliance, FBgn0039594 ) The gene snustorr is referred to in FlyBase by the symbol Dmel\snu (CG9990, FBgn0039594). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (all unique). FLYBASE GENE REPORT: DMEL\SIK3 Automatically Generated Summary (FlyBase) The gene Salt-inducible kinase 3 is referred to in FlyBase by the symbol Dmel\Sik3 (CG42856, FBgn0262103). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (5 unique). FLYBASE GENE REPORT: DMEL\CHIC The gene chickadee is referred to in FlyBase by the symbol Dmel\chic (CG9553, FBgn0000308). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is 2L:5972115..5981018. Its molecular function is described by: protein binding; actin monomer binding. FLYBASE REFERENCE REPORT: MOHLER, 1977, GENETICS 85: 259--272 Mohler, J.D. (1977). Developmental genetics of the Drosophila egg. I. Identification of 59 sex-linked cistrons with maternal effects on embryonic development. FLYBASE EXPERIMENTAL TOOL REPORT: GAL80TS The GAL80ts entry in FlyBase represents a temperature-sensitive version of the Saccharomyces cerevisiae GAL80 gene ( SGDID:S000004515 ). At the permissive temperature of 18C, GAL80ts protein is functional, acting as a negative regulator of the Saccharomyces cerevisiae GAL4 transcriptional activator, by binding to the GAL4 protein. At restrictive temperatures above 29C, FLYBASE REFERENCE REPORT: ROVANI ET AL., 2012, DEV. BIOL Rovani, M.K., Brachmann, C.B., Ramsay, G., Katzen, A.L. (2012). The dREAM/Myb-MuvB complex and Grim are key regulators of the programmed death of neural precursor FLYBASE REFERENCE REPORT: WOODFIELD ET AL., 2013, PLOS ONE Multiple genes involved in endocytosis and endosomal protein trafficking in Drosophila have been shown to function as neoplastic tumor suppressor genes (nTSGs), including Endosomal Sorting Complex Required for Transport-II (ESCRT-II) components vacuolar protein sorting 22 (vps22), vps25, and vps36. FLYBASE REFERENCE REPORT: DATE ET AL., 1998 Date, A., Satta, Y., Takahata, N., Chigusa, S.I. (1998). Evolutionary history and mechanism of the Drosophila cecropin gene family. Immunogenetics 47(6): 417--429. FLYBASE REFERENCE REPORT: YIN ET AL., 2017, BMC BIOL. 15(1 Zinc is an essential metal involved in many physiological processes. Previous work has identified a set of zinc transporters involved in Drosophila dietary zinc absorption. FLYBASE REFERENCE REPORT: ZHU ET AL., 2017, ELIFE 6: E22617 Genomic sequencing has implicated large numbers of genes and de novo mutations as potential disease risk factors. A high throughput in vivo model system is needed to FLYBASE REFERENCE REPORT: JAYANANDANAN ET AL., 2011, EMBO Jayanandanan, N., Gavis, E.R., Riechmann, V., Leptin, M. (2011). A genetic in vivo system to detect asymmetrically distributed RNA. EMBO Rep. 12(11): 1167--1174. FLYBASE HOMEPAGETOOLSSPECIESSEARCH/BROWSE PORTALSSUBMIT DATAOVERVIEWEXTERNAL RESOURCES Experiments with Drosophila for Biology Courses. Experiments with Drosophila for Biology Courses, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics FLYBASE GENE REPORT: DMEL\DPY dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and FLYBASE GENE REPORT: DMEL\MIR-14 Is expressed in organism. (Alliance, FBgn0262447 ) Automatically Generated Summary (FlyBase) The gene mir-14 stem loop is referred to in FlyBase by the symbol Dmel\mir-14 (CR43013, FBgn0262447). It is a miRNA_gene from Dmel. It has 3 annotated transcripts. FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE BALANCER/GENOTYPE VARIANT REPORT: DMEL\FM7A The Genome of Drosophila melanogaster. Rasooly et al., 1991, Genetics 129: 409--422. The lethal (1)TW6 cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-bindingdomain.
FLYBASE GENE REPORT: DMEL\GLURIA The gene Glutamate receptor IA is referred to in FlyBase by the symbol Dmel\GluRIA (CG8442, FBgn0004619). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6624032..6635059. FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE GENE REPORT: DMEL\SNU Is expressed in adult head; embryonic/larval trachea; and presumptive embryonic/larval system. (Alliance, FBgn0039594 ) The gene snustorr is referred to in FlyBase by the symbol Dmel\snu (CG9990, FBgn0039594). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (all unique). FLYBASE GENE REPORT: DMEL\ΑTUB67C The gene alpha-Tubulin at 67C is referred to in FlyBase by the symbol Dmel\alphaTub67C (CG8308, FBgn0087040). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9681268..9683370. FLYBASE HOMEPAGETOOLSSPECIESSEARCH/BROWSE PORTALSSUBMIT DATAOVERVIEWEXTERNAL RESOURCES Experiments with Drosophila for Biology Courses. Experiments with Drosophila for Biology Courses, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics FLYBASE GENE REPORT: DMEL\DPY dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and FLYBASE GENE REPORT: DMEL\MIR-14 Is expressed in organism. (Alliance, FBgn0262447 ) Automatically Generated Summary (FlyBase) The gene mir-14 stem loop is referred to in FlyBase by the symbol Dmel\mir-14 (CR43013, FBgn0262447). It is a miRNA_gene from Dmel. It has 3 annotated transcripts. FLYBASE GENE REPORT: DMEL\PATRONIN The gene Patronin is referred to in FlyBase by the symbol Dmel\Patronin (CG33130, FBgn0263197). It is a protein_coding_gene from Dmel. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:17519024..17535866. FLYBASE BALANCER/GENOTYPE VARIANT REPORT: DMEL\FM7A The Genome of Drosophila melanogaster. Rasooly et al., 1991, Genetics 129: 409--422. The lethal (1)TW6 cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-bindingdomain.
FLYBASE GENE REPORT: DMEL\GLURIA The gene Glutamate receptor IA is referred to in FlyBase by the symbol Dmel\GluRIA (CG8442, FBgn0004619). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6624032..6635059. FLYBASE INSERTION REPORT: DMEL\P{GAL4}REPO Expression is observed in glial cells. Expression is observed in all lateral glial cells. Expression is observed in in all ectodermally derived embryonic glial cells. Expression is observed in all ectodermally derived glial cells in the embryonic central and peripheral nervous systems. Insulin signaling mediates neurodegeneration in glioma. FLYBASE INSERTION REPORT: DMEL\P{CARYP}ATTP2 The P {CARY.attP}2 insertion is located between CG6310 and Mocs1 on chromosome 3L. SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. Potter, 2021.1.27, 5XQUAS-GCaMP6 constructs and insertions from Chris Potter. FLYBASE GENE REPORT: DMEL\SNU Is expressed in adult head; embryonic/larval trachea; and presumptive embryonic/larval system. (Alliance, FBgn0039594 ) The gene snustorr is referred to in FlyBase by the symbol Dmel\snu (CG9990, FBgn0039594). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (all unique). FLYBASE GENE REPORT: DMEL\ΑTUB67C The gene alpha-Tubulin at 67C is referred to in FlyBase by the symbol Dmel\alphaTub67C (CG8308, FBgn0087040). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9681268..9683370. FLYBASE REFERENCE REPORT: HAKES AND BRAND, 2020, ELIFE 9 Understanding the sequence of events leading to cancer relies in large part upon identifying the tumour cell of origin. Glioblastoma is the most malignant brain cancer but the early stages of disease progression remain elusive. FLYBASE STRAIN REPORT: CANTON-S Contains a recessive for multiple thoracic and scutellar bristles, which overlaps wild type in most flies but appears sporadically in strains partly derived from Canton-S. Selected by C. Bridges. Genetic variations of Drosophila melanogaster. FLYBASE GENE REPORT: DMEL\EMP The gene epithelial membrane protein is referred to in FlyBase by the symbol Dmel\emp (CG2727, FBgn0010435). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2R:24976456..24986070. FLYBASE GENE REPORT: DMEL\SS The gene spineless is referred to in FlyBase by the symbol Dmel\ss (CG6993, FBgn0003513). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:16374434..16403690. FLYBASE GENE REPORT: DMEL\OR22A The gene Odorant receptor 22a is referred to in FlyBase by the symbol Dmel\Or22a (CG12193, FBgn0026398). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:1520491..1522156. FLYBASE REFERENCE REPORT: ROVANI ET AL., 2012, DEV. BIOL Rovani, M.K., Brachmann, C.B., Ramsay, G., Katzen, A.L. (2012). The dREAM/Myb-MuvB complex and Grim are key regulators of the programmed death of neural precursor FLYBASE REFERENCE REPORT: MOHLER, 1977, GENETICS 85: 259--272 Mohler, J.D. (1977). Developmental genetics of the Drosophila egg. I. Identification of 59 sex-linked cistrons with maternal effects on embryonic development. FLYBASE REFERENCE REPORT: PERRIMON ET AL., 1985, GENETICS We have conducted a genetic and developmental analysis of genes within the 2C-D area of the X chromosome. Phenotypes of 33 mutations representing nine adjacent complementation groups including eight recessive lethals and one visible homeotic mutation (polyhomeotic) aredescribed.
FLYBASE REFERENCE REPORT: BABIC ET AL., 2015, J. NEUROSCI Mitochondria are dynamically transported in and out of neuronal processes to maintain neuronal excitability and synaptic function. In higher eukaryotes, the mitochondrial GTPase Miro binds Milton/TRAK adaptor proteins linking microtubule motors to mitochondria. FLYBASE REFERENCE REPORT: YIN ET AL., 2017, BMC BIOL. 15(1 Zinc is an essential metal involved in many physiological processes. Previous work has identified a set of zinc transporters involved in Drosophila dietary zinc absorption. FB2021_02, released April 13, 2021 A Database of _Drosophila_ Genes & Genomes FB2021_02, released April 13, 2021 A Database of _Drosophila_ Genes & GenomesMenu
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EXPERIMENTS WITH DROSOPHILA FOR BIOLOGY COURSES _Experiments with Drosophila for Biology Courses_, a fully open access e-book, edited by two experienced fly researchers and with contributions by many fly researchers in India, meets the need for development of new methods and paradigms for laboratory experiments at under- and post-graduate levels so that the young students and future academics can experience ‘life’. _— Apr 13, 2021._full commentary
U.S. IMPORT DOCUMENTS HAVE CHANGED! Regulations on importing transgenic organisms changed last year and new practices are now in effect. Documents for importing most _Drosophila melanogaster_ stocks are now much easier to obtain and use. Bloomington Drosophila Stock Center has webpages with detailedguidance
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