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VITADAO ANNOUNCES "LONGEVITY MOLECULE" RESEARCH PROJECT VitaDAO will use advanced machine learning to crunch the data from 1.04 billion prescriptions to understand the impact of drugs on human lifespan. VitaDAO, which frames itself as the “world’s first decentralized intellectual property collective” has announced its opening research project – The Longevity Molecule – which will beled by
AXA AND MICROSOFT LAUNCH ONE-STOP DIGITAL HEALTH PLATFORM Microsoft joins forces with AXA for ‘one-stop’ digital healthcare platform. One of Europe’s leading insurance companies AXA has announced it has formed a partnership with Microsoft and is launching an international digital health platform on the back of successful pilot schemes in Italy and Germany last year. FDA-APPROVED DRUG SLOWS CELLULAR AGING FDA-approved drug slows cellular aging. February 24, 2020. Scientists in the USA have discovered a drug to slow the cellular aging process. The only problem is its toxic side effects. Ah. Scientists at the Sanford Burnham Presbys Medical Discovery Institute and Harvard University have discovered one of the mechanisms that effects howcells age
USING STEM CELLS TO REVERSE AGING? A widely believed theory describes aging to be a result of the disruption in the balance between the breaking down of tissue and tissue rebuilding. Stem cells promote life extension by replacing the damaged and old cells, and have, therefore, emerged as a powerful tool in the fight against aging. However, as the years go by, the quantityand
BUILDING AN ARTIFICIAL IMMUNE SYSTEM A technology that could cleave glucosepane would potentially allow bound proteins to move freely again, and prevent age-related stiffening. “The clearest is developing catalysts that can cleave the glucosepane crosslinks to achieve advanced glycation endpoint (AGE) products,” saysSchafmeister.
NETWORKING AT A SENESCENT LEVEL ADVANCES FIGHT AGAINST AGING The Senolytic Therapy Network is advancing the fight against aging with outreach and research initiatives – we speak to a co-founder. The Senolytic Therapy Network (STN) was founded to serve as the premier organisation for studying and implementing senolytic therapies into clinical practice. With a firm belief that successful senolytic therapies are the necessary next step in advancing the JUVENESCENCE SCOOPS-UP NEW LONGEVITY IP IN SMART ACQUISITION Juvenescence CEO reveals why its deal with Portage is the smart choice for its longevity IP portfolio. Portage Biotech Inc, a clinical-stage immuno-oncology company accelerating research and development to overcome immune resistance, has announced the divestment of its three legacy businesses, Portage Pharmaceuticals Limited (PPL) and its subsidiaries, Portage Glasgow Ltd and EPIGENETIC REPROGRAMMING: THE ROAD TO REVERSING TIME Emerging evidence suggests that epigenetic reprogramming can actually reverse aging .Notably, a recent clinical study by Fahy et al. has shown that a 12-month treatment with recombinant human growth hormone decreased the epigenetic age by approximately two-and-a-half years; this landmark study was the first to confirm the possibility of reversing aging through epigenetic LONGEVITY.TECHNOLOGY Deep Longevity to partner with LifeHub & LifeClinic. Eleanor Garth -. May 18, 2021. 0. Deep Longevity adds LifeHub & LifeClinic to its growing longevity network, with physicians trained to interpret Deep Longevity’s biological age reports that incorporate multiple aging LONGEVITY ESCAPE VELOCITY BY 2035 Aubrey de Grey tells Longevity.Technology the revolution is coming, and everyone will be eligible. “I now think there is a 50% chance that we will reach longevity escape velocity by 2036. After that point (the “Methuselarity”), those who regularly receive the latest rejuvenation therapies will never suffer from age-related ill-healthat
VITADAO ANNOUNCES "LONGEVITY MOLECULE" RESEARCH PROJECT VitaDAO will use advanced machine learning to crunch the data from 1.04 billion prescriptions to understand the impact of drugs on human lifespan. VitaDAO, which frames itself as the “world’s first decentralized intellectual property collective” has announced its opening research project – The Longevity Molecule – which will beled by
AXA AND MICROSOFT LAUNCH ONE-STOP DIGITAL HEALTH PLATFORM Microsoft joins forces with AXA for ‘one-stop’ digital healthcare platform. One of Europe’s leading insurance companies AXA has announced it has formed a partnership with Microsoft and is launching an international digital health platform on the back of successful pilot schemes in Italy and Germany last year. FDA-APPROVED DRUG SLOWS CELLULAR AGING FDA-approved drug slows cellular aging. February 24, 2020. Scientists in the USA have discovered a drug to slow the cellular aging process. The only problem is its toxic side effects. Ah. Scientists at the Sanford Burnham Presbys Medical Discovery Institute and Harvard University have discovered one of the mechanisms that effects howcells age
USING STEM CELLS TO REVERSE AGING? A widely believed theory describes aging to be a result of the disruption in the balance between the breaking down of tissue and tissue rebuilding. Stem cells promote life extension by replacing the damaged and old cells, and have, therefore, emerged as a powerful tool in the fight against aging. However, as the years go by, the quantityand
BUILDING AN ARTIFICIAL IMMUNE SYSTEM A technology that could cleave glucosepane would potentially allow bound proteins to move freely again, and prevent age-related stiffening. “The clearest is developing catalysts that can cleave the glucosepane crosslinks to achieve advanced glycation endpoint (AGE) products,” saysSchafmeister.
NETWORKING AT A SENESCENT LEVEL ADVANCES FIGHT AGAINST AGING The Senolytic Therapy Network is advancing the fight against aging with outreach and research initiatives – we speak to a co-founder. The Senolytic Therapy Network (STN) was founded to serve as the premier organisation for studying and implementing senolytic therapies into clinical practice. With a firm belief that successful senolytic therapies are the necessary next step in advancing the JUVENESCENCE SCOOPS-UP NEW LONGEVITY IP IN SMART ACQUISITION Juvenescence CEO reveals why its deal with Portage is the smart choice for its longevity IP portfolio. Portage Biotech Inc, a clinical-stage immuno-oncology company accelerating research and development to overcome immune resistance, has announced the divestment of its three legacy businesses, Portage Pharmaceuticals Limited (PPL) and its subsidiaries, Portage Glasgow Ltd and EPIGENETIC REPROGRAMMING: THE ROAD TO REVERSING TIME Emerging evidence suggests that epigenetic reprogramming can actually reverse aging .Notably, a recent clinical study by Fahy et al. has shown that a 12-month treatment with recombinant human growth hormone decreased the epigenetic age by approximately two-and-a-half years; this landmark study was the first to confirm the possibility of reversing aging through epigenetic LONGEVITY.TECHNOLOGY Products we have tried and tested in our longevity store. Read our reviews before you purchase in the 'Product review' section. LONGEVITY SUPPLEMENTS REPORT: PROFILE OF JUVICELL, FOUNDER The idea for JUVICELL first originated in 2019 and was brought to fruition in 2020 by a US-German co-operation of scientists and like-minded investors with a strong personal interest in the space of longevity. Co-founder, Erin Sharoni (pictured), holds the strong ethos that “age is just a number” and is committed to prolonging andimproving
USING STEM CELLS TO REVERSE AGING? A widely believed theory describes aging to be a result of the disruption in the balance between the breaking down of tissue and tissue rebuilding. Stem cells promote life extension by replacing the damaged and old cells, and have, therefore, emerged as a powerful tool in the fight against aging. However, as the years go by, the quantityand
BUILDING AN ARTIFICIAL IMMUNE SYSTEM A technology that could cleave glucosepane would potentially allow bound proteins to move freely again, and prevent age-related stiffening. “The clearest is developing catalysts that can cleave the glucosepane crosslinks to achieve advanced glycation endpoint (AGE) products,” saysSchafmeister.
EPIGENETIC REPROGRAMMING: THE ROAD TO REVERSING TIME Emerging evidence suggests that epigenetic reprogramming can actually reverse aging .Notably, a recent clinical study by Fahy et al. has shown that a 12-month treatment with recombinant human growth hormone decreased the epigenetic age by approximately two-and-a-half years; this landmark study was the first to confirm the possibility of reversing aging through epigenetic REVIEW: BIOSENSE KETO MONITORING In my own words, the BIOSENSE is a hand-held, highly accurate, convenient device that quickly gives you a readout of your ketone levels simply by blowing into the mouthpiece for 3-5 seconds. Your ketone reading is then presented to you as ACEs, a unique unit of breath acetone provided by BIOSENSE. GO LONG. BREAKTHROUGH IN UNDERSTANDING PROTEIN SYNTHESIS AND AGING From biomarkers of aging to ribosome distribution, protein synthesis and aging are linked: a new paper reveals how. Making proteins is an enormous part of what a cell does; joining amino acids in a unique formation to create chains that are then folded in a specific way is a process that is complicated and tightly-controlled by cell machinery. EVERYTHING YOU NEED TO KNOW ABOUT SPERMIDINE SUPPLEMENTS Studies also suggest it can reduce the risk of cardiovascular disease and improve cognition. Spermidine has a neuroprotective effect against neuron damage caused by inflammation and ischemia and oxidative stress. Spermidine is a relatively new player on the scene, but is being increasingly used in supplement products. AGETECH INVESTMENT: "THERE IS EVERYTHING TO PLAY FOR The big gap identified in the focus group was investment to support early-stage innovation with a sweet spot for entrepreneurs of £50k – £750k. There is a strong argument for long-term opportunity, as there just needs to be more. Of everything! No real dominant brands have emerged so there is everything to play for. AGE-RELATED MACULAR DEGENERATION BIOTECH RAISES $148M Clinical-stage gene therapy company announces $148 million raised in Series C financing for age-related macular degeneration. London-based Gyroscope Therapeutics Limited, which focuses on treating diseases of the eye, announced today it has raised $148.0 million (£107.8 million) in a Series C financing led by Forbion’s GrowthOpportunities
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Longevity TV
THE SHEEKEY SCIENCE SHOW – SPERMIDINEPhil Newman
- June
4, 2021 0
Spermidine - autophagy & anti-aging research. Spermidine is a natural polyamine found in many foods...Read more
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June 4, 2021 0
The Wyss Center announces CE mark for its brain-computer interface software for communication, NeuroKey BCI, which enables communication in real time. The Wyss Center, which...Read more
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NEURONS AND AGING – PUTTING THE PIECES TOGETHER Victoria Barros Metlova- June
3, 2021 0
Mammoth review by Stefano Benvegnù summarises the role of nucleoplasmic transport as a major mechanism for homeostasis and neurotoxicity during healthy and pathological aging. Throughout...Read more
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June 2, 2021 0
New research from the Salk Institute spotlights molecular changes in underlying age-related muscle loss and signposts potential Yamanaka factor therapy. A research team at the...Read more
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RESEARCH INCREASES MICE LIFE EXPECTANCY BY 30%Eleanor Garth -
June 2, 2021 0
Bar-Ilan University researchers increase life expectancy in mice with protein SIRT6. The "fountain of youth" allows old mice to conduct thesame level of...
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BUILDING A VIRTUAL MODEL TO SOLVE HUMAN AGINGDanny Sullivan -
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Peter Fedichev explains how Gero is using AI and activity data to accelerate our understanding of human aging. We recently reported onAI firm Gero’s...
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Senolytic start-up establishes collaboration with Cedars-Sinai Medical Center to advance idiopathic pulmonary fibrosis program. Silicon Valley start-up Rubedo Life Sciences today announced a collaborationwith...
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MELATONIN SHOWN TO SLOW EXHAUSTION OF THE OVARIAN RESERVEDaragh Campbell
- May 31, 2021 0
Chinese researchers demonstrate that melatonin delays ovarian aging in mice by slowing down the exhaustion of the ovarian reserve. Previous studies have demonstrated that long-term...Read more
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Peter Fedichev explains how Gero is using AI and activity data to accelerate our understanding of human aging. We recently reported onAI firm Gero’s...
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WIND THE CLOCK BACK THREE YEARS… IN JUST EIGHT WEEKS?Eleanor Garth -
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New clinical trial demonstrates that mitigating DNA methylation with diet and lifestyle can produce a Horvath aging clock-measured biological age reduction of over...Read more
BIOMARKER LINKS NERVOUS SYSTEM DEGENERATION AND MORTALITYEleanor Garth -
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Nerve cell protein levels could be biomarker to predict mortality in individuals. Nervous system degeneration seems to be inevitably linked to mortality in older individuals...Read more
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INGENIOUS TOOL SPEEDS UP NEW MEDICINE DISCOVERYEleanor Garth -
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A digital tool that will make it cheaper, safer...Read more
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FIRST ALZHEIMER’S GENE THERAPY CLINICAL TRIAL BAGS $5MEleanor Garth -
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National Institute on Aging awards $5 million grant to...Read more
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DORIAN AND HITGEN TO COLLABORATE ON SENOTHERAPYEleanor Garth -
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Send in the senoblockers – Dorian and HitGen announce...Read more
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NEW AGING INSTITUTE WILL LEVERAGE INTELLECTUAL RESOURCESEleanor Garth -
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New Bakar Aging Research Institute in San Francisco is...Read more
INVESTMENT
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OISÍN SEED RAISE ADVANCES THERAPIES FOR DISEASES OF AGINGEleanor Garth -
May 28, 2021 0
Oisín Biotechnologies funding tops $9.5 million, with additional funding set to support preclinical development of its platform and investigational therapy for kidney and other age-related diseases.Seattle-based...
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DORIAN AND HITGEN TO COLLABORATE ON SENOTHERAPYEleanor Garth -
May 24, 2021 0
Send in the senoblockers – Dorian and HitGen announce a research collaboration focused on DNA-encoded library-based drug discovery for age-related diseases. HitGen, Inc today announced...Read more
AI/Digital
ANGERMAYER’S $120M FOR THE DISEASE OF THE CENTURY Danny Sullivan - May19, 2021 0
Investor states that mental health issues will be the "number one disease of the 21st century." Fresh from announcing his involvement ina $200 million...
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Investment
DYNO THERAPEUTICS CLOSES $100M TO ACCELERATE GENE THERAPYEleanor Garth -
May 14, 2021 0
Dyno Therapeutics closes $100 million Series A led by Andreessen Horowitz to accelerate AI-powered gene therapy platform. Dyno Therapeutics, Inc, a biotech applying AI to...Read more
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HUMA’S $130M RAISE WILL SCALE ITS DIGITAL HEALTH PLATFORMEleanor Garth -
May 12, 2021 0
With the goal of bringing proactive, predictive care to all, Huma has $130 million financing from leading health and technology companies. The investment arms of...Read more
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Elevant Prime dietary supplement contains a “high purity” form of NMN that has completed safety and toxicology testing. New York based health and wellness brand...Read more
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Christian Angermayer's Frontier Acquisition Corp. holds significant longevity interest with David Sinclair and Peter Attia as Co-Chairs of the Board. Frontier Acquisition Corporation, a special...Read more
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SPERMIDINE: THE MIND-ENHANCING SUPPLEMENTBeth Hyndman - May
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Scientists are finding that a high intake of dietary spermidine could slow down (or reverse) the brain aging process. Memory loss and slowerbrain function...
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Spermidine - autophagy & anti-aging research. Spermidine is a natural polyamine found in many foods you likely eat; mushrooms, broccoli, apples, nuts, soy, aged cheese...Read more
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Senotherapeutics are therapeutics strategies that target cellular senescence. They can work by killing senescent cells (senolytics), inhibiting the proinflammatory secretory phenotype of senescent cells(senomorphics)...
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SUPPLEMENTS
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LONGEVITY SUPPLEMENTS REPORT: VITALICEleanor Garth -
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Currently in stealth, Vitalic is on a mission to transition longevity from the early adopters on to a mass market through best-in-class marketing. Over the...Read more
LONGEVITY SUPPLEMENTS REPORT: QUICKSILVER SCIENTIFICEleanor Garth -
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Quicksilver – where supplements meet nanotech for fast, effective delivery. Over the last few weeks, we have brought you extracts of company profiles from our...Read more
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June 4, 2021 0
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Investment
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PCL Health monitors key vitals at home, providing caregivers with peace of mind and supporting aging-in-place. British start-up PCL Health (formerly Poonyah Care) is on...Read more
Investment
AGETECH FUND: FOCUS ON OVER-50S NOT MILLENNIALSDanny Sullivan -
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Founding partner of 1843 Capital targets AgeTech investment opportunities with $13 million fund. Connecticut-based early stage investment firm 1843 Capital values diversity highly, and seeks...Read more
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